Henderson-Hasselbalch Calculator

This is the first public release of the Henderson-Hasselbalch Calculator, a web-based tool that applies the classic acid-base equation to support clinical understanding and education. Designed for ease of use in both classroom and clinical revision contexts, the tool calculates missing values (pH, HCO₃⁻, or pCO₂) and identifies possible mixed acid-base disorders using patient input values.

Key Features

• Calculate pH, bicarbonate, or pCO₂ from two known values

• "Mixed disorder" mode compares measured and calculated pH

• Includes: - Step-by-step calculation - Educational quiz prompt - Clinical interpretation aid

• Fully browser-based, no install needed

• Mobile-friendly and accessible layout

Clinical Use

Useful for:

• Biomedical science education

• Medical and health science education

• Clinical revision

• Physiology instruction in acid-base balance

License

Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) Free to use and adapt for educational purposes with attribution. 🔗 Full License Terms

Citation

Price, C. L. (2025). Henderson-Hasselbalch Calculator (v1.0.0). Zenodo. https://doi.org/10.5281/zenodo.15545791